ODCs

Click node...

2 OMIM references -
2 associated genes
10 signs/symptoms

COMMON GENES: 1
PROTEIN INTERACTIONS: 2

1 OMIM reference -
3 associated genes
No signs/symptoms info

Hyperostosis corticalis generalisata

Retinopathy of prematurity


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	SOST LRP5	(0.68) (0.63)	LRP5 NDP

Citations in the biomedical literature:

Hyperostosis corticalis generalisata		Retinopathy of prematurity
	Synonym(s): - Van Buchem disease		Synonym(s): - ROP - Retrolental fibroplasia

	Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease		Classification (Orphanet): - Rare eye disease

	Classification (ICD10): - Diseases of the musculoskeletal system and connective tissue -		Classification (ICD10): - Diseases of the eye and adnexa -

	Epidemiological data: Class of prevalence: - Average age onset: - Average age of death: - Type of inheritance: autosomal recessive		Epidemiological data: (no data available)

	External references: 2 OMIM references - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: D012178

Hyperostosis corticalis generalisata
	Very frequent - Autosomal recessive inheritance - Clavicle absent / abnormal - Cortical anomaly / thick bone cortical layer - Dense / thickened skull / calvarium / cranial / facial hyperostosis - Enlarged diaphysis / diaphyses - Enlargment of jaw / large jaw - Osteosclerosis / osteopetrosis / bone condensation - Prognathism / prognathia Frequent - Facial palsy - Sensorineural deafness / hearing loss
Retinopathy of prematurity
(no data available)